288 datasets found
-
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of hippocampi from mice flown on the RRRM-2 mission
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
International Space Station conditions alter genomics, proteomics, and metabolomics in Aspergillus nidulans
National Aeronautics and Space Administration —
The first global genomic, proteomic, and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the... -
Federal
Transcription profiling of rat response to changes in developmental stage - 3 types of tissue, 3 gravity conditions, 2 developmental conditions
National Aeronautics and Space Administration —
Transcriptional crosstalk between mammary gland, liver and adipose tissue Experiment Overall Design: Pregnant and Lactating rats exposed to 3 gravity conditions -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (flow cytometry)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
Translating fundamental biological discoveries from NASA Space Biology program into health risk from space flights has been an ongoing challenge. We propose to use... -
Federal
Rodent Research-3-CASIS: Mouse retina transcriptomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Effects of microgravity on human iPSC-derived neural organoids on the International Space Station - dopaminergic organoids
National Aeronautics and Space Administration —
Research conducted on the International Space Station (ISS) in low-Earth orbit (LEO) has shown the effects of microgravity on multiple organs. To investigate the... -
Federal
Persistence of Escherichia coli in the microbiomes of mizuna mustard (Brassica rapa var. japonica) - does seed sanitization matter?
National Aeronautics and Space Administration —
Seed sanitization via chemical processes removes/reduces microbes from the external surfaces of the seed and thereby could have an impact on the plants' health or... -
Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG01B
National Aeronautics and Space Administration —
Lettuce crops grown in the Veggie payload aboard ISS, harvested and returned for chemical, microbiological and molecular analysis -
Federal
Transcriptomics analysis of etiolated Arabidopsis thaliana seedlings in response to microgravity
National Aeronautics and Space Administration —
Gene expression profile of two-week-old etiolated Arabidopsis seedlings under microgravity on board space flight BRIC16 were compared with ground grown control in... -
Federal
Quantitative evaluation of bioaerosols in different particle size fractions collected on the International Space Station (ISS)
National Aeronautics and Space Administration —
Exposure to bioaerosols can negatively impact human health. On the International Space Station (ISS) this exposure differs to that on Earth due to lack of... -
Federal
Microbial Observatory (ISS-MO): Indoor microbiome study of the International Space Station surfaces
National Aeronautics and Space Administration —
Presented here is the environmental microbiome study of the International Space Station surfaces. The environmental samples were collected with the polyester wipes... -
Federal
Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influenced by Immune System Transcriptome Modifications from Splenic Tissue
National Aeronautics and Space Administration —
Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological... -
Federal
Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station
National Aeronautics and Space Administration —
Genomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS)... -
Federal
Utilizing the KSC Fixation Tube to Conduct Human-Tended Plant Biology Experiments on a Suborbital Spaceflight
National Aeronautics and Space Administration —
Suborbital spaceflights now enable human-tended research investigating short-term gravitational effects in biological systems, eliminating the need for complex... -
Federal
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight [plasma proteomics]
National Aeronautics and Space Administration —
Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in... -
Federal
Transcriptional analysis of thymus from mice flown on the RR-6 Mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Comparison of the spaceflight transcriptome of four commonly used Arabidopsis thaliana ecotypes
National Aeronautics and Space Administration —
This experiment compared the spaceflight transcriptomes of four commonly used natural variants (ecotypes) of Arabidopsis thaliana using RNAseq. In nature, Arabidopsis... -
Federal
Draft genome sequence of Klebsiella quasipneumoniae subsp. similipneumoniae strain IF3SW-P1 isolated from the International Space Station
National Aeronautics and Space Administration —
In 2015, the Advanced Resistive Exercise Device (ARED) foot panel on the International Space Station (ISS) was sampled to identify culturable microorganisms. The... -
Federal
Effects of 32 Days Aboard the ISS on Quadricep Tendon Nanomechanics (Quadricep femoris tendon, RR-1 and Atomic Force Microscopy)
National Aeronautics and Space Administration —
Collagen is an essential component of connective tissue and plays a crucial role in elasticity, stability, and force distribution. While the adaptations of tendon to...
288 datasets found