Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station
Genomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS) is reported, along with a comparison to the experimentally established strain ATCC 1015. Whole-genome sequencing of JSC-093350089 revealed enhanced genetic variance when compared to publicly available sequences of A. niger strains. Analysis of the isolate’s proteome revealed significant differences in the molecular phenotype of JSC-093350089, including increased abundance of proteins involved in the A. niger starvation response, oxidative stress resistance, cell wall integrity and modulation, and nutrient acquisition. Together, these data reveal the existence of a distinct strain of A. niger onboard the ISS and provide insight into the molecular phenotype that is selected for by melanized fungal species inhabiting spacecraft environments.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "026:00" ] |
| contactPoint |
{ "fn": "Open Science Data Repository Help Desk", "@type": "vcard:Contact", "hasEmail": "mailto:arc-dl-osdr-help@mail.nasa.gov" } |
| description | Genomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS) is reported, along with a comparison to the experimentally established strain ATCC 1015. Whole-genome sequencing of JSC-093350089 revealed enhanced genetic variance when compared to publicly available sequences of A. niger strains. Analysis of the isolate’s proteome revealed significant differences in the molecular phenotype of JSC-093350089, including increased abundance of proteins involved in the A. niger starvation response, oxidative stress resistance, cell wall integrity and modulation, and nutrient acquisition. Together, these data reveal the existence of a distinct strain of A. niger onboard the ISS and provide insight into the molecular phenotype that is selected for by melanized fungal species inhabiting spacecraft environments. |
| distribution |
[ { "@type": "dcat:Distribution", "format": "BIN", "mediaType": "application/octet-stream", "downloadURL": "http://purl.bioontology.org/ontology/NCBITAXON/5061" }, { "@type": "dcat:Distribution", "format": "BIN", "mediaType": "application/octet-stream", "downloadURL": "https://osdr.nasa.gov/bio/repo/data/studies/OSD-260" }, { "@type": "dcat:Distribution", "format": "BIN", "mediaType": "application/octet-stream", "downloadURL": "https://www.ebi.ac.uk/pride/archive/projects/PXD008588" } ] |
| identifier | 10.26030/7c74-jk03 |
| keyword |
[ "biological-and-physical-sciences", "genelab", "nasa" ] |
| license | https://www.usa.gov/government-works |
| modified | 2026-08-10 |
| programCode |
[ "026:000" ] |
| publisher |
{ "name": "Open Science Data Repository", "@type": "org:Organization" } |
| theme |
[ "Biological and Physical Sciences" ] |
| title | Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station |
