288 datasets found
-
Federal
Response of human lymphoblastoid cells to HZE (iron ions) or gamma-rays
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiated cells with cells exposed 24 hours previously to 1.67 Gy HZE (1 GeV/amu iron ions... -
Federal
Correlated Gene and Protein Expression in heads from Drosophila reared in microgravity
National Aeronautics and Space Administration —
Omics analyses of RNA and protein isolated from heads of microgravity reared adult Drosophila. -
Federal
Real-time quantitative PCR analysis of human cardiovascular progenitor cells flown aboard the International Space Station
National Aeronautics and Space Administration —
Adult and neonatal human cardiovacular progenitor cell clonal populations were flown aboard the ISS for 12 days prior to fixation in RNAprotect. Gene expression... -
Federal
Comparing RNA-Seq and microarray gene expression data in two zones of the Arabidopsis root apex relevant to spaceflight.
National Aeronautics and Space Administration —
Premise of the study: The root apex is an important region involved in environmental sensing, but comprises a very small part of the root. Obtaining root apex... -
Federal
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats (Grip; force transducer)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Transcriptional analysis of dorsal skin from mice flown on the RR-5 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-5 (RR-5) study was to evaluate bone loss in mice during spaceflight and to determine if treatment with a modified version of NEL-... -
Federal
Transcriptional profiling of heart tissue from mice flown on the RRRM-2 mission
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Effects of 5-Ion Beam Irradiation and Hindlimb Unloading on Metabolic Pathways in Plasma and Brain of Behaviorally Tested WAG/Rij Rats
National Aeronautics and Space Administration —
A limitation of simulated space radiation studies is that radiation exposure is not the only environmental challenge astronauts face during missions. Therefore, we... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [iron]
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1... -
Federal
Space environmental factor impacts upon murine colon microbiota and mucosal homeostasis
National Aeronautics and Space Administration —
We report how high and low linear energy transfer (LET) radiation, microgravity, and elevated dietary iron affect colon microbiota (determined by 16S rDNA... -
Federal
Metagenome profiling of feces from mice flown on the RRRM-1 mission
National Aeronautics and Space Administration —
In Rodent Research Reference Mission-1 (RRRM-1), forty female BALB/cAnNTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Transcriptional analysis of dorsal skin from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Lower eukaryotic isolates belonging to class Tremellomycetes isolated from International Space Station Genome sequencing and assembly
National Aeronautics and Space Administration —
Genome sequencing and assembly of lower Eukaryotic isolates belonging to class Tremellomycetes isolated from International Space Station -
Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG03A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Densely Ionizing Radiation Effects on the Microenvironment Promote Aggressive Trp53 Null Mammary Carcinomas
National Aeronautics and Space Administration —
Densely ionizing radiation is a major component of the space radiation environment and has potentially greater carcinogenic effect compared to sparsely ionizing... -
Federal
Gene expression profiling for spaceflight induced-neuroinflammation in the mouse brain
National Aeronautics and Space Administration —
The health risk from spaceflight-induced neuronal damage and potential adverse neurovascular effects is a chief concern. More recently, it has been proposed that... -
Federal
Transcriptional profiling of soleus muscle from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 mission (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of... -
Federal
Heart Flies - effect of microgravity on heart function in Drosophila
National Aeronautics and Space Administration —
Canton S laboratory wildtype lines (Bloomington Stock Center) and a K+ channel mutant seizure (seizurets1, a gift from Dr. Barry Ganetsky, published in Titus et al.,... -
Federal
Transcriptional profiling of tibialis anterior muscle from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 mission (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of... -
Federal
Effects of low dose space radiation exposures on the splenic metabolome
National Aeronautics and Space Administration —
Future space missions will include return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides...
288 datasets found