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Federal
The genetic structure of recombinant inbred mice: high-resolution consensus maps for complex trait analysis
U.S. Department of Health & Human Services —
Background Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in... -
Federal
Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients
U.S. Department of Health & Human Services —
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to... -
Federal
Auto-protective redox buffering systems in stimulated macrophages
U.S. Department of Health & Human Services —
Background Macrophages, upon encounter with micro-organisms or stimulated by cytokines, produce various effector molecules aimed at destroying the foreign agents and... -
Federal
Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)
U.S. Department of Health & Human Services —
Background Although much is known about the regulation of osteoclast (OC) formation and activity, little is known about OC senescence. In particular, the fate of of... -
Federal
Association of mesenchymal cells and immunoglobulins with differentiating epithelial cells
U.S. Department of Health & Human Services —
Background Mesenchymal-epithelial interactions play an important role in the physiology and pathology of epithelial tissues. Mesenchymal cells either associate with... -
Federal
Accessing and distributing EMBL data using CORBA (common object request broker architecture)
U.S. Department of Health & Human Services —
Background: The EMBL Nucleotide Sequence Database is a comprehensive database of DNA and RNA sequences and related information traditionally made available in flat-... -
Federal
The evaluation of yeast derivatives as adjuvants for the immune response to the Bm86 antigen in cattle
U.S. Department of Health & Human Services —
Background The Gavac™ vaccine against the cattle tick Boophilus microplus has proven its efficacy in a large number of controlled and field experiments. However, this... -
Federal
To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?
U.S. Department of Health & Human Services —
Background Patients with Alzheimer's disease experience a progressive loss of cognitive function, and the ability to independently perform activities of daily life.... -
Federal
Identification and preliminary characterization of mouse
U.S. Department of Health & Human Services —
Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely... -
Federal
Receptorphin: A conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells
U.S. Department of Health & Human Services —
Background In addition to endogenous opioids, a number of peptide sequences, derived from endogenous (hemorphins, alphaS1-casomorphin), and exogenous proteins... -
Federal
Survey of transcripts in the adult
U.S. Department of Health & Human Services —
Background: Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then... -
Federal
NEAT: a domain duplicated in genes near the components of a putative Fe
U.S. Department of Health & Human Services —
Iron uptake from the host is essential for bacteria that infect animals. A protein domain has been identified that appears in variable copy number in bacterial genes... -
Federal
Chromosomal mapping, gene structure and characterization of the human and murine
U.S. Department of Health & Human Services —
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in... -
Federal
Effects on respiratory function of the head-down position and the complete covering of the face by drapes during insertion of the monitoring catheters in the cardiosurgical patient
U.S. Department of Health & Human Services —
Background: We evaluated the effect on the respiratory gas exchange of the 30° head-down position and the complete covering of the face by sterile drapes. These are... -
Federal
Human papilloma viruses and cervical tumours: mapping of integration sites and analysis of adjacent cellular sequences
U.S. Department of Health & Human Services —
Background In cervical tumours the integration of human papilloma viruses (HPV) transcripts often results in the generation of transcripts that consist of hybrids of... -
Federal
Genetic epidemiology: Psoriatic arthritis
U.S. Department of Health & Human Services —
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis... -
Federal
Prevention and diagnosis of venous thromboembolism in critically ill patients: a Canadian survey
U.S. Department of Health & Human Services —
Background Venous thromboembolism (VTE) confers considerable morbidity and mortality in hospitalized patients, although few studies have focused on the critically ill... -
Federal
Crystal structure of LIR-2 (ILT4) at 1.8 Å: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18
U.S. Department of Health & Human Services —
Background Leukocyte Immunoglobulin-like Receptor-1 (LIR-1) and LIR-2 (also known as ILT2 and ILT4 respectively) are highly related cell surface receptors that bind a... -
Federal
Apolipoprotein C3 SstI polymorphism and triglyceride levels in Asian Indians
U.S. Department of Health & Human Services —
Background A close association between Sst I polymorphism in the 3' untranslated region of the apolipoproteinC3 (APOC3) gene and levels of plasma triglycerides (TG)... -
Federal
A family of putative K
U.S. Department of Health & Human Services —
Background Prior to this report, members of the inward rectifier family, or Kir, have been found only in eukaryotes. Like most K+ channels, the pore-forming part of...