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Federal
Assessing utility of thyroid in vitro screening assays through comparisons to observed impacts in vivo
U.S. Environmental Protection Agency —
Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro... -
Federal
Selecting a Minimal set of Androgen Receptor Assays for Screening Chemicals
U.S. Environmental Protection Agency —
Screening certain environmental chemicals for their ability to interact with endocrine targets, including the androgen receptor (AR), is an important global concern.... -
Federal
Limited chemical structural diversity found to modulate thyroid hormone receptor in the Tox21 chemical library
U.S. Environmental Protection Agency —
The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist... -
Federal
Prioritization of chemicals for effects on steroidogenesis using an integrated statistical approach to high-throughput H295R data
U.S. Environmental Protection Agency —
HT-H295R data was downloaded using the ToxCast pipeline (tcpl) R package and is publicly available. Multi-concentration level 0 data from invitrodb (version 3.1) were... -
Federal
High-throughput AR dimerization assay identifies androgen disrupting chemicals and metabolites
U.S. Environmental Protection Agency —
Repository for supplemental files and code for paper titled "High-throughput AR Dimerization Assay Identifies Androgen Disrupting Chemicals and Metabolites", 2022....