99 datasets found for "environment"
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Federal
Impact of spaceflight on gene expression in cultured human mesenchymal stem/stromal cell
National Aeronautics and Space Administration —
With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight?
National Aeronautics and Space Administration —
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural... -
Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03E
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7) in Response to Spaceflight. [RNA-Seq]
National Aeronautics and Space Administration —
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants adaption to environmental... -
Federal
Exposure to elevated relative humidity in laboratory chambers alters fungal gene expression in dust from the International Space Station (ISS)
National Aeronautics and Space Administration —
Microbes are present in all occupied indoor environments, including the International Space Station (ISS). An unexpected ventilation system failure may lead to... -
Federal
Light has a principal role in the Arabidopsis transcriptomic response to the spaceflight environment
National Aeronautics and Space Administration —
The Characterizing Arabidopsis Root Attractions (CARA) spaceflight experiment provides comparative transcriptome analyses of plants grown in both light and dark... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
Translating fundamental biological discoveries from NASA Space Biology program into health risk from space flights has been an ongoing challenge. We propose to use... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment, and then we ask whether undifferentiated cells, cells... -
Federal
Comparative Genomic Analysis of Klebsiella Exposed to Various Space Conditions at the International Space Station
National Aeronautics and Space Administration —
Due to the bacteria's evolved resistance to radiation, Klebsiella poses a great threat to not only planetary protection, but also to the integrity of future... -
Federal
Whole metagenome profiles of particulates collected from the International Space Station.
National Aeronautics and Space Administration —
The microbial composition of the International Space Station (ISS) environment is of critical interest due to potential impact of its constituents on human health and... -
Federal
Transcriptional profiling of colon from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection
National Aeronautics and Space Administration —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
Federal
Effects of 32 Days Aboard the ISS on Gastrocnemius Tendon Nanomechanics (Gastrocnemius tendon, RR-1 and Atomic Force Microscopy)
National Aeronautics and Space Administration —
Collagen is an essential component of connective tissue and plays a crucial role in elasticity, stability, and force distribution. While the adaptations of tendon to... -
Federal
Transcriptional profiling of roots and shoots from Brachypodium distachyon seedlings flown on the ISS
National Aeronautics and Space Administration —
Most major cereal grain crops are monocots. Yet, most investigations of plant adaptation to the spaceflight environment have been carried out on the dicotyledonous... -
Federal
Transcriptional and Post transcriptional Regulation of Seedling Development in Microgravity
National Aeronautics and Space Administration —
The project focuses on understanding the transcriptional and post-transcriptional mechanisms that regulate early seedling development in spaceflight and microgravity.... -
Federal
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 1]
National Aeronautics and Space Administration —
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology, yet the apparent components of hypobaria are stresses... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cerebral Cortex
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7) in Response to Spaceflight. [Bisulfite-Seq]
National Aeronautics and Space Administration —
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants’ adaption to environmental... -
Federal
Transcriptional profiling of thymus tissue from rats flown on the SLS-2 mission
National Aeronautics and Space Administration —
The Spacelab Life Sciences (SLS) program was a series of payloads that used the facilities of an entire Spacelab module to conduct a variety of life science...
99 datasets found for "environment"