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Federal
Differentiating Pathway-Specific From Nonspecific Effects in High-Throughput Toxicity Data: A Foundation for Prioritizing Adverse Outcome Pathway Development
U.S. Environmental Protection Agency —
Previous work identified a ‘cytotoxic burst’ (CTB) phenomenon wherein large numbers of the ToxCast assays begin to respond at or near test chemical concentrations... -
Federal
Extracting and benchmarking emerging adverse outcome pathway knowledge
U.S. Environmental Protection Agency —
A collection of R scripts useful for extracting and analyzing adverse outcome pathway network data from the adverse outcome pathway wiki (aopwiki.org). This dataset... -
Federal
Adverse Outcome Pathway Networks II: Network Analytics
U.S. Environmental Protection Agency —
The data set provides a set of txt files and cytoscape files that were used to construct the example AOP networks included in the paper. Additionally, a supplementary... -
Federal
Defining the Taxonomic Domain of Applicability for Mammalian-Based High-Throughput Screening Assays
U.S. Environmental Protection Agency —
Final Data SeqAPASS v3.0.zip contains datasets from Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool versions 3.0 for all 497 proteins...