22 datasets found for "arrest"
-
Federal
Cellular senescence:ex vivop53-dependent asymmetric cell kinetics
U.S. Department of Health & Human Services —
Cellular senescence is a defining property of euploid cells in culture [1,2]. Cultures derived from cells explanted from tissues of a variety of animal species... -
Federal
Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity
U.S. Department of Health & Human Services —
Background The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth... -
Federal
Clinical applicability of molecular biology: the case of the long QT syndrome
U.S. Department of Health & Human Services —
The clinical applicability of molecular cardiology has been questioned at length and by many clinical investigators. The congenital long QT syndrome (LQTS) provides... -
Federal
The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia
U.S. Department of Health & Human Services —
Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental... -
Federal
Effects of an angiotensin II antagonist on organ perfusion during the post-resuscitation phase in pigs
U.S. Department of Health & Human Services —
Background: The aim of this study was to compare pre-arrest and post-resuscitation organ perfusion values and to investigate whether, during the post-resuscitation... -
Federal
Mitotic death: a mechanism of survival? A review
U.S. Department of Health & Human Services —
Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its... -
Federal
Retroviral transfer of the p16INK4a cDNA inhibits C6 glioma formation in Wistar rats
U.S. Department of Health & Human Services —
Background The p16INK4A gene product halts cell proliferation by preventing phosphorylation of the Rb protein. The p16INK4a gene is often deleted in human... -
Federal
Multipletelophase arrest bypassed (tab)mutants alleviate the essential requirement for Cdc15 in exit from mitosis inS. cerevisiae
U.S. Department of Health & Human Services —
The Mitotic Exit Network (MEN) proteins – including the protein kinase Cdc15 and the protein phosphatase Cdc14 – are essential for exit from mitosis inSaccharomyces... -
Federal
Expression of c-
U.S. Department of Health & Human Services —
Background A study was undertaken to resolve preliminary conflicting results on the proliferation of leukemia cells observed with different c-myc antisense... -
Federal
Hypothermia and neurologic outcome in patients following cardiac arrest: should we be hot to cool off our patients?
U.S. Department of Health & Human Services —
Hypothermia as a protectant of neurologic function in the treatment of cardiac arrest patients, although not a new concept, is now supported by two recent randomized,... -
Federal
Antenatal infection/inflammation and postnatal lung maturation and injury
U.S. Department of Health & Human Services —
Chorioamnionitis is frequently associated with preterm deliveries before 30 weeks gestation. Chorioamnionitis correlates both with an increased risk of... -
Federal
Patent AT-E400176-T1: [Translated] INACTIVATED OOCYTES AS CYTOPLASMIC RECEPTORS FOR NUCLEAR TRANSFER
U.S. Department of Health & Human Services —
A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division.... -
Federal
Anti-TNF-α therapy as a clinical intervention for periprosthetic osteolysis
U.S. Department of Health & Human Services —
Aseptic loosening of total joint arthroplastics due to periprosthetic osteolysis is a frequent cause of implant failure. The absence of clinical interventions to... -
Federal
The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution
U.S. Department of Health & Human Services —
Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing... -
Federal
CCAAT/Enhancer Binding Protein alpha uses distinct domains to prolong pituitary cells in the Growth 1 and DNA Synthesis phases of the cell cycle
U.S. Department of Health & Human Services —
Background A number of transcription factors coordinate differentiation by simultaneously regulating gene expression and cell proliferation. CCAAT/enhancer binding... -
Federal
Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data
U.S. Department of Health & Human Services —
Introduction Strychnine poisoning is uncommon, and in most severe cases, the patient dies before reaching hospital. The management of strychnine poisoning is well... -
Federal
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
U.S. Department of Health & Human Services —
Background The cyclin-dependent kinase inhibitor p27 is a putative tumor suppressor that is downregulated in the majority of human prostate cancers. The mechanism of... -
Federal
Possible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fields
U.S. Department of Health & Human Services —
Background The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part... -
Federal
Genetic stabilization by p53 involves growth regulatory and repair pathways
U.S. Department of Health & Human Services —
p53 performs a plethora of activities, which are directed towards the maintenance of the genomic integrity and constitute its universal role as a tumor suppressor.... -
Federal
Equipment review: Intrahospital transport of critically ill patients
U.S. Department of Health & Human Services —
Background This review on the current literature of the intrahospital transport of critically ill patients addresses type and incidence of adverse effects, risk...
22 datasets found for "arrest"