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Federal
Binding of the baculovirus very late expression factor 1 (VLF-1) to different DNA structures
U.S. Department of Health & Human Services —
Background Baculovirus genomes encode a gene called very late expression factor 1 (VLF-1) that is a member of the integrase (Int) family of proteins. In this report... -
Federal
Insertion of a small peptide of six amino acids into the β7–β8 loop of the p51 subunit of HIV-1 reverse transcriptase perturbs the heterodimer and affects its activities
U.S. Department of Health & Human Services —
Background HIV-1 RT is a heterodimeric enzyme, comprising of the p66 and p51 subunits. Earlier, we have shown that the β7-β8 loop of p51 is a key structural element... -
Federal
Lipoprotein profile in older patients with vascular dementia and Alzheimer's disease
U.S. Department of Health & Human Services —
Background Some alterations of the lipoprotein profile have been associated with cerebrovascular disease. Recently, it has been suggested that cerebrovascular disease... -
Federal
The liver is a common non-exocrine target in primary Sjögren's syndrome: A retrospective review
U.S. Department of Health & Human Services —
Background The autoimmune destruction of exocrine glands that defines primary Sjögren's syndrome (1°SS) often extends to non-exocrine organs including the liver. We... -
Federal
Patent AT-E399795-T1: [Translated] METHOD FOR PRODUCING IMPROVED DEXTRAN-HEMOGLOBIN CONJUGATES
U.S. Department of Health & Human Services —
An hemoglobin (Hb)-Dextran (Dx) conjugate having a molecular weight between 50 kd and 500 kD provides a blood substitute that results in acceptable erythrocyte... -
Federal
Research Article: BMC Ecology
U.S. Department of Health & Human Services —
Background In spite of very low nutrient concentrations in its vicinity – both column and pore waters-, the Posidonia oceanica of the Revellata Bay displays high... -
Federal
Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate and its relation to clinical variables in inflammatory arthritis
U.S. Department of Health & Human Services —
Hypothalamic–pituitary–adrenal underactivity has been reported in rheumatoid arthritis (RA). This phenomenon has implications with regard to the pathogenesis and... -
Federal
Do published guidelines for evaluation of Irritable Bowel Syndrome reflect practice?
U.S. Department of Health & Human Services —
Background The only US guidelines listed in the National Guideline Warehouse for the diagnosis of Irritable Bowel Syndrome (IBS) are the expert opinion guidelines... -
Federal
Effects of Cu
U.S. Department of Health & Human Services —
Background Heavy metals, especially copper, nickel, lead and zinc, have adverse effects on terrestrial and in aquatic environments. However, their impact can vary... -
Federal
Correlation of the score for subjective pain with physical disability, clinical and radiographic scores in recent onset rheumatoid arthritis
U.S. Department of Health & Human Services —
Background To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen... -
Federal
Probing the importance and potential roles of the binding of the PH-domain protein Boi1 to acidic phospholipids
U.S. Department of Health & Human Services —
Background The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src...