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Federal
Use of antihypertensive medications in pregnancy and the risk of adverse perinatal outcomes: McMaster Outcome Study of Hypertension In Pregnancy 2 (
U.S. Department of Health & Human Services —
Background Uncertainty remains about the potential harmful effects of antihypertensive therapy on the developing fetus, especially for beta-blockers (βb). Methods We... -
Federal
Patent AT-E401656-T1: [Translated] PRODUCTION OF HIGH OR MEDIUM VOLTAGE WINDINGS FOR OIL-FILLED TRANSFORMERS AND WINDINGS PRODUCED THEREFORE
U.S. Department of Health & Human Services —
The invention relates to oil-immersed power or electric power distribution transformers for which the size of the high (or medium) voltage windings is to be reduced.... -
Federal
Results of a phase-I/II randomized, masked, placebo-controlled trial of recombinant human interleukin-11 (rhIL-11) in the treatment of subjects with active rheumatoid arthritis
U.S. Department of Health & Human Services —
Interleukin-11 (IL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of... -
Federal
Are women and providers satisfied with antenatal care? Views on a standard and a simplified, evidence-based model of care in four developing countries
U.S. Department of Health & Human Services —
Background This study assessed women and providers' satisfaction with a new evidence-based antenatal care (ANC) model within the WHO randomized trial conducted in... -
Federal
Cardiac rehabilitation: a comprehensive review
U.S. Department of Health & Human Services —
Cardiac rehabilitation (CR) is a commonly used treatment for men and women with cardiovascular disease. To date, no single study has conclusively demonstrated a... -
Federal
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology
U.S. Department of Health & Human Services —
Background An association between mumps-measles-rubella (MMR) vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to... -
Federal
Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial
U.S. Department of Health & Human Services —
Inhibition of the sodium-hydrogen exchanger (NHE) is a powerful experimental tool to inhibit sodium and calcium accumulation within the ischemic myocyte and halt... -
Federal
Patent AT-E40171-T1: [Translated] HAND OPERATED SECURITY CONTROL FOR ELECTRIC LOCKS, PARTICULARLY FOR MOTOR VEHICLES.
U.S. Department of Health & Human Services —
Claims for the contracting states : BE, CH, DE, GB, IT, LI, NL, SE Safety manual control for locks with an electric control or others, which includes, generally near... -
Federal
The lung as a route for systemic delivery of therapeutic proteins and peptides
U.S. Department of Health & Human Services —
The large surface area, good vascularization, immense capacity for solute exchange and ultra-thinness of the alveolar epithelium are unique features of the lung that... -
Federal
Reporting of adverse drug reactions in randomised controlled trials – a systematic survey
U.S. Department of Health & Human Services —
Background Decisions on treatment are guided, not only by the potential for benefit, but also by the nature and severity of adverse drug reactions. However, some... -
Federal
Lactate: A key metabolite in the intercellular metabolic interplay
U.S. Department of Health & Human Services —
Most physicians involved in intensive care consider lactate solely as a deleterious metabolite, responsible for high morbidity and bad prognosis in severe patients.... -
Federal
Ablation of atrial fibrillation: a procedure come of age?
U.S. Department of Health & Human Services —
Various approaches for catheter ablation of focal initiators of atrial fibrillation or the substrate for maintaining atrial fibrillation have evolved over the past 5... -
Federal
Equipment review: Intrahospital transport of critically ill patients
U.S. Department of Health & Human Services —
Background This review on the current literature of the intrahospital transport of critically ill patients addresses type and incidence of adverse effects, risk... -
Federal
Use of a rapid arterial blood gas analyzer to estimate blood hemoglobin concentration among critically ill adults
U.S. Department of Health & Human Services —
Objective To evaluate whether measurement of the hemoglobin (Hb) concentration with a blood gas analyzer approximates that determined by a conventional coulter... -
Federal
Patent AT-E401488-T1: [Translated] LADDER WITH PLATFORM AND FOLDING TUBULAR SAFETY DEVICES, ESPECIALLY FOR EXTENSION LADDER
U.S. Department of Health & Human Services —
The ladder has a balustrade tube (13) associated to a lower platform (15) and including lower and upper rails (17, 19) arranged at about 0.5 mm and 1 mm from the... -
Federal
Noninferiority trials
U.S. Department of Health & Human Services —
In one of the biggest dilemmas facing cardiovascular clinical research, clinical trials are increasingly being required to show benefits on clinical end-points rather... -
Federal
Prone positioning does not affect cannula function during extracorporeal membrane oxygenation or continuous renal replacement therapy
U.S. Department of Health & Human Services —
Introduction Prone positioning in respiratory failure has been shown to be a useful adjunct in the treatment of severe hypoxia. However, the prone position can result... -
Federal
Field trial with oral vaccination of dogs against rabies in the Philippines
U.S. Department of Health & Human Services —
Background The potential role of oral vaccination of dogs against rabies in the Philippines was investigated in terms of safety and efficacy. Methods Prior to the... -
Federal
Induction of apoptosis in rat peripheral blood lymphocytes by the anticancer drug CI-994 (acetyldinaline)
U.S. Department of Health & Human Services —
Abstract CI-994 (acetyldinaline) is an investigational anticancer drug currently in clinical trials. In preclinical safety studies in rats and dogs, CI-994 resulted... -
Federal
Medical errors: how the US Government is addressing the problem
U.S. Department of Health & Human Services —
November's Institute of Medicine (IOM) report on medical errors has sparked debate among US health policy makers as to the appropriate response to the problem....