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Federal
Chromosomal mapping, gene structure and characterization of the human and murine
U.S. Department of Health & Human Services —
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in... -
Federal
An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use
U.S. Department of Health & Human Services —
Background Management of thalassemia major requires patients to have life-long access to a treatment regimen of regular blood transfusions coupled with iron chelation... -
Federal
Policy mapping for establishing a national emergency health policy for Nigeria
U.S. Department of Health & Human Services —
Background The number of potential life years lost due to accidents and injuries though poorly studied has resulted in tremendous economic and social loss to Nigeria.... -
Federal
Use of antihypertensive medications in pregnancy and the risk of adverse perinatal outcomes: McMaster Outcome Study of Hypertension In Pregnancy 2 (
U.S. Department of Health & Human Services —
Background Uncertainty remains about the potential harmful effects of antihypertensive therapy on the developing fetus, especially for beta-blockers (βb). Methods We... -
Federal
Can Australian general practitioners effectively screen for diabetic retinopathy? A pilot study
U.S. Department of Health & Human Services —
Background Diabetes has been identified as one of the national health priority areas in Australia. After 20 years of diabetes most patients can be expected to develop... -
Federal
Design and performance of a multi-centre randomised controlled trial and economic evaluation of joint tele-consultations [ISRCTN54264250]
U.S. Department of Health & Human Services —
Background Appropriate information flow is crucial to the care of patients, particularly at the interface between primary and secondary care. Communication problems... -
Federal
Immune ablation and stem-cell therapy in autoimmune disease: Clinical experience
U.S. Department of Health & Human Services —
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an... -
Federal
Detection ofMycobacterium avium subspecies paratuberculosisspecific IS900 insertion sequences in bulk-tank milk samples obtained from different regions throughout Switzerland
U.S. Department of Health & Human Services —
SinceMycobacterium aviumsubspeciesparatuberculosis(MAP) was isolated from intestinal tissue of a human patient suffering Crohn's disease, a controversial discussion... -
Federal
Blood substitutes: Haemoglobin therapeutics in clinical practice
U.S. Department of Health & Human Services —
Early approaches to the development of oxygen carriers involved the use of stroma-free hemoglobin solutions. These solutions did not require blood typing or... -
Federal
Biventricular pacing in heart failure: update on results from clinical trials
U.S. Department of Health & Human Services —
Biventricular pacing or resynchronisation therapy is a non-pharmacological therapy for patients with chronic heart failure. Since being originally described in 1994,... -
Federal
Bone loss: Epidemiology of bone loss
U.S. Department of Health & Human Services —
Bone loss occurs when the cellular events of bone formation are quantitatively larger than bone formation. This manuscript discusses the measurement of bone loss,... -
Federal
The baboon (
U.S. Department of Health & Human Services —
Background As novel endovascular strategies are developed for treating neurological disease, there is an increasing need to evaluate these techniques in relevant... -
Federal
Drug-induced and postnatal hypothyroidism impairs the accumulation of diacylglycerol in liver and liver cell plasma membranes
U.S. Department of Health & Human Services —
Background Thyroid hormones are well known modulators of signal transduction. The effect of hyper- and hypo-thyroidism on diacylglycerol/protein kinase C (DAG/PKC)... -
Federal
Impact of nosocomial pneumonia on the outcome of mechanically-ventilated patients
U.S. Department of Health & Human Services —
Background: Nosocomial pneumonia (NP) is a common complication in mechanically-ventilated patients and is considered to be one of the most common causes of morbidity... -
Federal
Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.
U.S. Department of Health & Human Services —
Background Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of... -
Federal
Occurrence of leu
U.S. Department of Health & Human Services —
Background Many investigations have reported that advantageous mutations occurred more frequently under selective conditions than those under non-selective... -
Federal
Accuracy of prognosis estimates by four palliative care teams: a prospective cohort study
U.S. Department of Health & Human Services —
Background Prognosis estimates are used to access services, but are often inaccurate. This study aimed to determine the accuracy of giving a prognosis range. Methods... -
Federal
Diagnostic strategies for C-reactive protein
U.S. Department of Health & Human Services —
Background Serum C-reactive protein (CRP) has been identified in prospective epidemiological research as an independent risk marker for cardiovascular disease. In... -
Federal
Transjugular renal biopsy in high-risk patients: an American case series
U.S. Department of Health & Human Services —
Background In the United States, transjugular renal biopsies using the Quickcore™ side cut needle system have previously been described primarily for transjugular... -
Federal
Model-based cluster analysis of microarray gene-expression data
U.S. Department of Health & Human Services —
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data....