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Federal
GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors
U.S. Department of Health & Human Services —
Background Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often... -
Federal
Analysis of fluorescently labeled substance P analogs: binding, imaging and receptor activation
U.S. Department of Health & Human Services —
Background Substance P (SP) is a peptide neurotransmitter found in central and peripheral nerves. SP is involved in the control of smooth muscle, inflammation and... -
Federal
SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines
U.S. Department of Health & Human Services —
Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to... -
Federal
General Practitioners' views on the provision of nicotine replacement therapy and bupropion
U.S. Department of Health & Human Services —
Background Nicotine replacement therapies (NRT) and a new drug, bupropion, are licensed in several countries as aids to smoking cessation. General practitioners (GPs)... -
Federal
Systematic review of the use of honey as a wound dressing
U.S. Department of Health & Human Services —
Objective To investigate topical honey in superficial burns and wounds though a systematic review of randomised controlled trials. Data sources Cochrane Library,... -
Federal
Effect of hemofiltration filter adsorption on circulating IL-6 levels in septic rats
U.S. Department of Health & Human Services —
Introduction Hemofiltration may modulate the inflammatory response in sepsis through a variety of mechanisms. We sought to distinguish clearance from adsorption as... -
Federal
Priority setting for new technologies in medicine: A transdisciplinary study
U.S. Department of Health & Human Services —
Background Decision makers in health care organizations struggle with how to set priorities for new technologies in medicine. Traditional approaches to priority... -
Federal
Influence of CSP 310 and CSP 310-like proteins from cereals on mitochondrial energetic activity and lipid peroxidation
U.S. Department of Health & Human Services —
Background The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. Mitochondria are... -
Federal
Which treatment for low back pain? A factorial randomised controlled trial comparing intravenous analgesics with oral analgesics in the emergency department and a centrally acting muscle relaxant with placebo over three days [ISRCTN09719705]
U.S. Department of Health & Human Services —
Background About two thirds of adults suffer from backpain at some time during their life. In the emergency room many patients with acute back pain are treated with... -
Federal
Tumour necrosis factor-α production in fibrosing alveolitis is macrophage subset specific
U.S. Department of Health & Human Services —
Background Previous studies have revealed that tumour necrosis factor (TNF)-α is upregulated in fibrosing alveolitis (FA) in humans. The aim of this study was to... -
Federal
The effects of isatin (indole-2, 3-dione) on pituitary adenylate cyclase-activating polypeptide-induced hyperthermia in rats
U.S. Department of Health & Human Services —
Background Previous studies have demonstrated that centrally administered natriuretic peptides and pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38)... -
Federal
Lactoferrin and free secretory component of human milk inhibit the adhesion of enteropathogenic
U.S. Department of Health & Human Services —
Background Diarrhoea caused by Escherichia coli is an important cause of infant morbidity and mortality in developing countries. Enteropathogenic Escherichia coli... -
Federal
Low systemic vascular resistance: differential diagnosis and outcome
U.S. Department of Health & Human Services —
Objective: To determine the frequency and prognosis of the various causes of low systemic vascular resistance (SVR). Design: Analysis of consecutive patients over a... -
Federal
Inter-rater agreement in the scoring of abstracts submitted to a primary care research conference
U.S. Department of Health & Human Services —
Background Checklists for peer review aim to guide referees when assessing the quality of papers, but little evidence exists on the extent to which referees agree... -
Federal
Single session endoscopic management of intrinsic ureteropelvic junction obstruction and concomitant renal stone disease in a child: a case report
U.S. Department of Health & Human Services —
Background Percutaneous nephrolithotomy is a well known therapeutic modality for stone diseases of childhood. Antegrade and retrograde endopyelotomies are also well... -
Federal
S-carboxymethylcysteine in the treatment of glue ear: quantitative systematic review
U.S. Department of Health & Human Services —
Objective To establish the clinical relevance of S-carboxymethylcysteine in the treatment of glue ear in children using measures approximating those saving a child... -
Federal
Asymmetric interactions in the adenosine-binding pockets of the MS2 coat protein dimer
U.S. Department of Health & Human Services —
Background The X-ray structure of the MS2 coat protein-operator RNA complex reveals the existence of quasi-synmetric interactions of adenosines -4 and -10 in pockets... -
Federal
A new prototype of an electronic jet-ventilator and its humidification system
U.S. Department of Health & Human Services —
Background: Adequate humidification in long-term jet ventilation is a critical aspect in terms of clinical safety. Aim: To assess a prototype of an electronic jet-... -
Federal
High-resolution physical map for chromosome 16q12.1-q13, the Blau syndrome locus
U.S. Department of Health & Human Services —
Background The Blau syndrome (MIM 186580), an autosomal dominant granulomatous disease, was previously mapped to chromosome 16p12-q21. However, inconsistent physical... -
Federal
What is the optimal prophylaxis for treatment of cardiac allograft vasculopathy?
U.S. Department of Health & Human Services —
Coronary artery disease in the transplanted heart, also known as cardiac allograft vasculopathy (CAV), is one of the major causes of mortality late after...