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Federal
Locations of several novel 2'-
U.S. Department of Health & Human Services —
Background Ribose 2'-O-methylation, the most common nucleotide modification in mammalian rRNA, is directed by the C/D box small nucleolar RNAs (snoRNAs). Thus far,... -
Federal
Enhanced immunogenicity of a functional enzyme by T cell epitope modification
U.S. Department of Health & Human Services —
Background T helper epitopes are necessary for the induction of high titers of antigen-specific IgG antibodies. We are interested in the epitope modification of... -
Federal
Predictors of positive health in disability pensioners: a population-based questionnaire study using Positive Odds Ratio
U.S. Department of Health & Human Services —
Background Determinants of ill-health have been studied far more than determinants of good and improving health. Health promotion measures are important even among... -
Federal
Debate: The slippery slope of surrogate outcomes
U.S. Department of Health & Human Services —
Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes.... -
Federal
Pro/con clinical debate: Are steroids useful in the management of patients with septic shock?
U.S. Department of Health & Human Services —
Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of... -
Federal
The efficacy of chemical agents in cleaning and disinfection programs
U.S. Department of Health & Human Services —
Background Due to the growing number of outbreaks of infection in hospital nurseries, it becomes essential to set up a sanitation program that indicates that the... -
Federal
Hamster oocyte membrane potential and ion permeability vary with preantral cumulus cell attachment and developmental stage
U.S. Department of Health & Human Services —
Background In vitro maturation of mammalian oocytes is an area of great interest due to its potential application in the treatment of infertility. The morphological... -
Federal
The new anti-actin agent dihydrohalichondramide reveals fenestrae-forming centers in hepatic endothelial cells
U.S. Department of Health & Human Services —
Background Liver sinusoidal endothelial cells (LSECs) react to different anti-actin agents by increasing their number of fenestrae. A new structure related to... -
Federal
Phylogenetic relationships and taxonomic position of
U.S. Department of Health & Human Services —
Background Little is known about phytoplankton communities inhabiting low pH environments such as volcanic and geothermal sites or acidic waters. Only specialised... -
Federal
Primary renal carcinoid natural history of the disease for ten years: case report
U.S. Department of Health & Human Services —
Background Primary renal carcinoid is extremely rare and there are few reports on the natural history of the disease. Case presentation A 68-year-old male with a... -
Federal
Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery
U.S. Department of Health & Human Services —
Background Dinitrosyl nonheme-iron complexes can appear in cells and tissues overproducing nitric oxide. It is believed that due to their chemical nature these... -
Federal
Model-supported estimation of mortality rates in Baltic cod (
U.S. Department of Health & Human Services —
Background Changes in the survival-rate during the larval phase may strongly influence the recruitment level in marine fish species. During the larval phase different... -
Federal
Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon: Correction
U.S. Department of Health & Human Services —
Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or... -
Federal
Compound 527356: 16,20-Dimethyl-tritriacontyl cyanide
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: 17,21-dimethyltetratriacontanenitrile. Molecular Formula: C36H71N. Molecular Weight: 518.0. This dataset... -
Federal
Mutational analysis of Peroxiredoxin IV: exclusion of a positional candidate for multinodular goitre
U.S. Department of Health & Human Services —
Background Multinodular goitre (MNG) is a common disorder characterised by an enlargement of the thyroid, occurring as a compensatory response to hormonogenesis... -
Federal
Impact of rhinitis on airway inflammation: biological and therapeutic implications
U.S. Department of Health & Human Services —
There is increasing evidence for a close link between the upper and the lower respiratory tracts and the fact that rhinitis has an important impact on asthma. Several... -
Federal
Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis
U.S. Department of Health & Human Services —
Background: Increased serum levels of procalcitonin (ProCT) and its component peptides have been reported in humans with sepsis. Using a hamster model of bacterial... -
Federal
Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line
U.S. Department of Health & Human Services —
Background Tetracycline-regulated systems have been used to control the expression of heterologous genes in such diverse organisms as yeast, plants, flies and mice.... -
Federal
Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis
U.S. Department of Health & Human Services —
Nidovirus subgenomic mRNAs contain a leader sequence derived from the 5′ end of the genome fused to different sequences (‘bodies’) derived from the 3′ end. Their... -
Federal
Rational use of computerized protocols in the intensive care unit
U.S. Department of Health & Human Services —
Excess information in complex ICU environments exceeds human decision making limits, increasing the likelihood of clinical errors. Explicit decision-support tools...