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Federal
What is the optimal prophylaxis for treatment of cardiac allograft vasculopathy?
U.S. Department of Health & Human Services —
Coronary artery disease in the transplanted heart, also known as cardiac allograft vasculopathy (CAV), is one of the major causes of mortality late after... -
Federal
Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases
U.S. Department of Health & Human Services —
Chromosomal aberrations were comparatively assessed in nuclei extracted from synovial tissue, primary-culture (P-0) synovial cells, and early-passage synovial... -
Federal
Molecular archeology of an SP100 splice variant revisited: dating the retrotranscription and
U.S. Department of Health & Human Services —
Background SP100 is a nuclear protein that displays a number of alternative splice variants. In Old World monkeys, apes and humans one of these variants is extended... -
Federal
Assessment of tissue oxygen tension: comparison of dynamic fluorescence quenching and polarographic electrode technique
U.S. Department of Health & Human Services —
Introduction and methods Dynamic fluorescence quenching is a technique that may overcome some of the limitations associated with measurement of tissue partial oxygen... -
Federal
Atrial natriuretic peptide infusion and nitric oxide inhalation in patients with acute respiratory distress syndrome
U.S. Department of Health & Human Services —
Aim: To study the effects of infusion of atrial natriuretic peptide (ANP) versus the inhalation of nitric oxide (NO) in patients with an early acute respiratory... -
Federal
Improvement of Drosophila acetylcholinesterase stability by elimination of a free cysteine
U.S. Department of Health & Human Services —
Background Acetylcholinesterase is irreversibly inhibited by organophosphate and carbamate insecticides allowing its use for residue detection with biosensors.... -
Federal
Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial
U.S. Department of Health & Human Services —
Inhibition of the sodium-hydrogen exchanger (NHE) is a powerful experimental tool to inhibit sodium and calcium accumulation within the ischemic myocyte and halt... -
Federal
Cost effectiveness in treating ventilator-associated pneumonia
U.S. Department of Health & Human Services —
Ventilator-associated pneumonia is a common illness in intensive care unit patients. The costs of management are increased when infection involves resistant... -
Federal
Deconstructing patient centred communication and uncovering shared decision making: an observational study
U.S. Department of Health & Human Services —
Background Patient centred communication (PCC) has been described as a method for doctor-patient communication. The principles of shared decision making (SDM) have... -
Federal
Clinical trials in developing countries: Discussions at the '9th International Symposium on Long Term Clinical Trials', London, UK, 19-20 June 2000
U.S. Department of Health & Human Services —
This symposium provided a useful forum for the discussion of issues relating to the design and conduct of clinical trials. There is a need for greater awareness of... -
Federal
IFN-γ production in response to
U.S. Department of Health & Human Services —
IFN-γ was measured in supernatants after in vitro stimulation of peripheral blood mononuclear cells with collagen type II (CII), purified protein derivative or... -
Federal
Cultured Kaposi's sarcoma tumor cells exhibit a chemokine receptor repertoire that does not allow infection by HIV-1
U.S. Department of Health & Human Services —
Background HIV-1 is known to play a critical role in the pathogenesis of AIDS-associated Kaposi's sarcoma (KS). However, it remains controversial whether KS cells are... -
Federal
Imiquimod for the treatment of genital warts: a quantitative systematic review
U.S. Department of Health & Human Services —
Objective To review published randomised controlled trials to assess the benefit and harm of imiquimod in the treatment of external genital warts. Data sources... -
Federal
The use of breast conserving surgery: linking insurance claims with tumor registry data
U.S. Department of Health & Human Services —
Background The purpose of this study was to use insurance claims and tumor registry data to examine determinants of breast conserving surgery (BCS) in women with... -
Federal
Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial [ISRCTN19943732]
U.S. Department of Health & Human Services —
The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK... -
Federal
The minisequencing method: a simple strategy for genetic screening of MEN 2 families
U.S. Department of Health & Human Services —
Background Multiple endocrine neoplasia type 2 is an autosomal dominant disorder. MEN 2A is characterized by medullary thyroid carcinoma, pheochromocytoma and... -
Federal
Selective alteration of gene expression in response to natural and synthetic retinoids.
U.S. Department of Health & Human Services —
Background Retinoids are very potent inducers of cellular differentiation and apoptosis, and are efficient anti-tumoral agents. Synthetic retinoids are designed to... -
Federal
Preoperative Acute Normovolaemic Hemodilution (ANH) in combination with Hypotensive Epidural Anaesthesia (HEA) during knee arthroplasty surgery. No effect on transfusion rate. A randomized controlled trial [ISRCTN87597684]
U.S. Department of Health & Human Services —
Background Hypotensive epidural anaesthesia (HEA) combines a high epidural anaesthesia, performing a sympathetic blockade, with low-dose iv-infusion of epinephrine to... -
Federal
Effects of an angiotensin II antagonist on organ perfusion during the post-resuscitation phase in pigs
U.S. Department of Health & Human Services —
Background: The aim of this study was to compare pre-arrest and post-resuscitation organ perfusion values and to investigate whether, during the post-resuscitation... -
Federal
Field trial with oral vaccination of dogs against rabies in the Philippines
U.S. Department of Health & Human Services —
Background The potential role of oral vaccination of dogs against rabies in the Philippines was investigated in terms of safety and efficacy. Methods Prior to the...