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Federal
Use of the direct puncture technique in management of capillaro-venous malformations: case report
U.S. Department of Health & Human Services —
Background Preoperative devascularization of the capillaro-venous malformations located in the aero-digestive tract is important for surgeons, to minimize blood loss... -
Federal
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis
U.S. Department of Health & Human Services —
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression... -
Federal
Long-term experience with implanted intrathecal drug administration systems for failed back syndrome and chronic mechanical low back pain
U.S. Department of Health & Human Services —
Background Continuous intrathecal drug delivery has been shown in open studies to improve pain and quality of life in those with intractable back pain who have had... -
Federal
Withdrawal of cerivastatin from the world market
U.S. Department of Health & Human Services —
Cerivastatin was recently withdrawn from the market because of 52 deaths attributed to drug-related rhabdomyolysis that lead to kidney failure. The risk was found to... -
Federal
Phorbol esters and CAMP differentially regulate the expression of CD4 and CD8 in human thymocytes
U.S. Department of Health & Human Services —
Background Intrathymic development and selection of the T lymphocyte repertoire is restricted by the interactions of the T cell antigen receptor and CD4 or CD8 co-... -
Federal
The burden of pediatric HIV/AIDS in Constanta, Romania: a cross-sectional study
U.S. Department of Health & Human Services —
Background By 1990, 94 percent of the acquired immunodeficiency syndrome (AIDS) cases in Romania were in children less than 13 years of age. The majority of the cases... -
Federal
Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?
U.S. Department of Health & Human Services —
The cellular and molecular mechanisms that are involved in airway hyper-responsiveness are unclear. Current studies suggest that tumor necrosis factor (TNF)-α, a... -
Federal
A new era in hypertension research: discussing the findings of ALLHAT
U.S. Department of Health & Human Services —
The key question in hypertension research today is, "Does it matter how elevated blood pressure is lowered?" The Antihypertensive and Lipid-Lowering Treatment to... -
Federal
The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease
U.S. Department of Health & Human Services —
The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to... -
Federal
A regulator of G Protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion
U.S. Department of Health & Human Services —
Background Luteinizing hormone secreted by the anterior pituitary gland regulates gonadal function. Luteinizing hormone secretion is regulated both by alterations in... -
Federal
Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
U.S. Department of Health & Human Services —
In the present study, we searched for mutant PTEN transcripts in aggressive rheumatoid arthritis synovial fibroblasts (RA-SF) and studied the expression of PTEN in... -
Federal
Potential role and chronology of abnormal expression of the Deleted in Colon Cancer (DCC) and the p53 proteins in the development of gastric cancer
U.S. Department of Health & Human Services —
Background Loss of activity of tumor suppressor genes is considered a fundamental step in a genetic model of carcinogenesis. Altered expression of the p53 and the... -
Federal
The use of breast conserving surgery: linking insurance claims with tumor registry data
U.S. Department of Health & Human Services —
Background The purpose of this study was to use insurance claims and tumor registry data to examine determinants of breast conserving surgery (BCS) in women with... -
Federal
Variations in chemoprophylaxis for meningococcal disease: a retrospective case note review, analysis of routine prescribing data and questionnaire of general practitioners
U.S. Department of Health & Human Services —
Background Invasive meningococcal disease is a significant cause of mortality and morbidity in the UK. Administration of chemoprophylaxis to close contacts reduces... -
Federal
Attitudes of the Japanese public and doctors towards use of archived information and samples without informed consent: Preliminary findings based on focus group interviews
U.S. Department of Health & Human Services —
Background The purpose of this study is to explore laypersons' attitudes toward the use of archived (existing) materials such as medical records and biological... -
Federal
Lack of autoantibody production associated with cytomegalovirus infection
U.S. Department of Health & Human Services —
To confirm an association between cytomegalovirus (CMV) infection and the presence of antibodies to Smith (Sm), to ribonucleoprotein (RNP), and to a component of the... -
Federal
Genomic approaches to research in lung cancer
U.S. Department of Health & Human Services —
The medical research community is experiencing a marked increase in the amount of information available on genomic sequences and genes expressed by humans and other... -
Federal
Desferrioxamine decreases NAD redox potential of intact red blood cells: evidence for desferrioxamine as an inducer of oxidant stress in red blood cells
U.S. Department of Health & Human Services —
Background Desferrioxamine (DFO) is an important iron chelating agent. It has also been thought of as an agent with anti-oxidant potential as it chelates ferric iron... -
Federal
Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture — primary culture cells markedly differ from fourth-passage cells
U.S. Department of Health & Human Services —
To reduce culture artifacts by conventional repeated passaging and long-term culture in vitro, the isolation of synovial fibroblasts (SFB) was attempted from... -
Federal
Research Article: BMC Genomics
U.S. Department of Health & Human Services —
Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The...