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Background High-density oligonucleotide arrays (HDONAs) are a powerful tool for assessing differential mRNA expression levels. To establish the statistical significance of an observed...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 01:53 PM -
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however, hampered efforts to...
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Background Current methodology often cannot distinguish second primary breast cancers from multifocal disease, a potentially important distinction for clinical management. In the present...
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Genome-composition analysis using microarrays can be used to categorize genes into 'present' and 'divergent' categories. This involves selecting a signal value that is used as a cutoff to...
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Background It has been recognized that replicates of arrays (or spots) may be necessary for reliably detecting differentially expressed genes in microarray experiments. However, the...
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A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human...
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Background Methods for extracting useful information from the datasets produced by microarray experiments are at present of much interest. Here we present new methods for finding gene...
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A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:15 AM -
Within the fold: assessing differential expression measures and reproducibility in microarray assays
Fold-change' cutoffs have been widely used in microarray assays to identify genes that are differentially expressed. More accurate measures are required to identify high-confidence sets of genes...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: September 07, 2025 at 09:32 AM -
A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:14 AM -
Background A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe...
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Parasitic helminths of the genusSchistosomamate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important pathological consequences of the...
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An analysis of numerous Drosophila microarray experiments reveals that the genome has many large groups of adjacent genes that are expressed similarly but are not functionally related.
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Background A key assumption in the analysis of microarray data is that the quantified signal intensities are linearly related to the expression levels of the corresponding genes. To test...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: September 07, 2025 at 07:37 AM
