These data represent laboratory reflectance measurements conducted on a suite of sandstone, tuffaceous mudstone and claystone rocks and sediment, which are known host and source materials for roll front Uranium deposits mined throughout the South Texas Coastal Plains. Visible through Near Infrared through Shortwave Infrared (~0.4 - 2.5 microns) reflectance were measured using an artificial light source attached to an Analytical Spectral Devices (ASD) spectrometer. A total of 125 spectra were measured and analyzed, representing samples from nine former open-pit mine sites excavating rocks from four different mapped geologic units, including rocks and sediments from the Jackson Group, Catahoula, Oakville and Goliad Formations. These spectra represent averages of a larger set of 569 random surface reflectance measurements, most of which yielded redundant spectral shapes, which were reduced to a smaller but more representative dataset. The data were obtained in support of studies aimed at mapping uranium mine waste features throughout portions Karnes, Atascosa and Live Oak counties along the South Texas Coastal Plain. Each of the nine mine sites are geolocated within the included point shapefiles. Geographic coordinates are based on those provided within the Uranium assessment report and accompanying GIS supplemental data provided in the following associated reference: Hall, S.M., Mihalasky, M.J., Tureck, K.R., Hammarstrom, J.M., and Hannon, M.T., 2017. Genetic and grade and tonnage models for sandstone-hosted roll-type uranium deposits, Texas Coastal Plain, USA. Ore Geology Reviews, volume 80, pages 716-753.