The National Drought Mitigation Center produces VegDRI in collaboration with the US Geological Survey's (USGS) Center for Earth Resources Observation and Science (EROS), and the High Plains Regional Climate Center (HPRCC), with sponsorship from the US Department of Agriculture's (USDA) Risk Management Agency (RMA). Main researchers working on VegDRI are Dr. Brian Wardlow and Dr. Tsegaye Tadesse at the NDMC, and Jesslyn Brown with the USGS, and Dr. Yingxin Gu with ASRC Research and Technology Solutions, contractor for the USGS at EROS.

VegDRI maps are produced every two weeks and provide regional to sub-county scale information about drought's effects on vegetation. In 2006, VegDRI covered seven states in the Northern Great Plains (CO, KS, MT, NE, ND, SD, and WY). It expanded across eight more states in 2007 to cover the rest of the Great Plains (NM, OK, MO, and TX) and parts of the Upper Midwest (IA, IL, MN, and WI). VegDRI expanded to include the western U.S. in 2008 (WA, ID, OR, UT, CA, AZ, NV). In May 2009 VegDRI began depicting the eastern states as well, covering the entire conterminous 48-state area.