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Transcriptomic data (GSE199233) and CEBs data (from Blake et al. 2020) for maternal and fetal endpoints following gestational exposure to PFOA or GenX
Maternal and fetal liver gene expression and pathway changes following exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA) during gestation.
This dataset is associated with the following publication:
Blake, B., C. Miller, H. Nguyen, V. Chappell, T. Phan, D. Phadke, M. Balik-Meisner, D. Mav, R. Shah, and S. Fenton. Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. Elsevier Science Ltd, New York, NY, USA, 248: 114314, (2022).
Resources
2 resources available
-
https://cebs.niehs.nih.gov/cebs/paper/14946
FILE -
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199233
FILE
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Bevin Blake", "hasEmail": "mailto:blake.bevin@epa.gov" } |
| description | Maternal and fetal liver gene expression and pathway changes following exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA) during gestation. This dataset is associated with the following publication: Blake, B., C. Miller, H. Nguyen, V. Chappell, T. Phan, D. Phadke, M. Balik-Meisner, D. Mav, R. Shah, and S. Fenton. Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. Elsevier Science Ltd, New York, NY, USA, 248: 114314, (2022). |
| distribution |
[ { "title": "https://cebs.niehs.nih.gov/cebs/paper/14946", "accessURL": "https://cebs.niehs.nih.gov/cebs/paper/14946" }, { "title": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199233", "accessURL": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199233" } ] |
| identifier | https://doi.org/10.23719/1531698 |
| keyword |
[ "Adverse Outcome Pathways (AOPs)", "Children's Environmental Health", "Drinking water contaminants", "PFAS", "children's health" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html |
| modified | 2022-11-17 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1016/j.ecoenv.2022.114314", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742811" ] |
| rights |
null
|
| title | Transcriptomic data (GSE199233) and CEBs data (from Blake et al. 2020) for maternal and fetal endpoints following gestational exposure to PFOA or GenX |
