Geologic structure and isopach maps were constructed by interpreting over 19,890 trackline kilometers of co-located multichannel boomer, sparker and chirp seismic reflection profiles from the continental shelf of the Delmarva Peninsula, including Maryland and Virginia state waters. In this region, Brothers and others (2020) interpret 12 seismic units and 11 regional unconformities. They interpret the infilled channels as Late Tertiary and Quaternary courses of the Susquehanna, Potomac, Rappahannock, York and James Rivers and tributaries, in addition to a broad drainage system. These regional unconformities form a composite unconformity interpreted as the Quaternary-Tertiary (Q-T) unconformity. A depth to Tertiary (Uqt) and total Quaternary sediment thickness (Q) isopach are included with this data release. Other products in this data release include thickness of an early Pleistocene unit (Qbd), thickness of a Pleistocene highstand system tract (Q2), thickness of a post last glacial maximum (LGM) fluvial/estuarine unit (Qcch), thickness of Holocene to modern marine sediment (Qmn), depth to the base of the Persimmons Point and Ocean City paleochannels (U4), depth to the base of the Exmore and Belle Haven paleochannels (U6), depth to the base of the Eastville paleochannel and tributaries (U8), depth to the base (fluvial unconformity) of the Cape Charles paleochannel and tributary paleochannels (fluvial unconformity, U10) and the base (tidal ravinement) of associated Holocene tidal and back-barrier deposits (tidal ravinement surface, U10.5).