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Targeted RNA-sequencing of aged FFPE liver tissue data

Metadata Updated: July 18, 2022

Gene expression data on >20 year-old, paired frozen and archival FFPE liver samples generated using targeted resequencing (TempO-Seq) and whole-genome RNA-sequencing methods. Samples were originally collected from male mice exposed to a reference chemical (dichloroacetic acid, DCA) at 0, 198, 313 and 427 mg/kg-day, (n=6/dose) by drinking water for 6 days. Portions of this dataset are inaccessible because: Including all of these files on ScienceHub would exceed the 1 Gb limit. They can be accessed through the following means: The data is stored on the L: Drive. Information on all of the files and file paths are indicated in the 20210923_Readme.xlsx file uploaded with the data. Format: Excel files, tab delimited files, csv files, and sequencing FASTQ files.

This dataset is associated with the following publication: Cannizzo, M., C. Wood, S. Hester, and L. Wehmas. Case study: Targeted RNA-sequencing of aged formalin-fixed paraffin-embedded samples for understanding chemical mode of action. Toxicology Reports. Elsevier B.V., Amsterdam, NETHERLANDS, 9: 883-894, (2022).

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

Downloads & Resources



Metadata Created Date July 18, 2022
Metadata Updated Date July 18, 2022

Metadata Source

Harvested from EPA ScienceHub

Additional Metadata

Resource Type Dataset
Metadata Created Date July 18, 2022
Metadata Updated Date July 18, 2022
Publisher U.S. EPA Office of Research and Development (ORD)
Data Last Modified 2021-09-23
Public Access Level public
Bureau Code 020:00
Schema Version
Harvest Object Id c7dce564-33c5-4a5c-9145-9076ab2ef96d
Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
Harvest Source Title EPA ScienceHub
Program Code 020:000
Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents
Source Datajson Identifier True
Source Hash 2f72a7a3b48e3369e8325388d49f7c102dfb55d5
Source Schema Version 1.1

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