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Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Catalog Last Checked: April 21, 2026 at 08:07 PM | Dataset Last Updated: October 28, 2024
We used systematic evidence map methods to summarize the available epidemiological and animal bioassay evidence for an expanded set of ~15,000 PFAS that were identified as PFAS by EPA's Center for Computational Toxicology and Exposure (CCTE). This work is a continuation of our previous 2022 and 2024 SEMs that inventoried evidence on a separate set of ~500 PFAS (Carlson et al, 2022, https://doi.org/10.1289/EHP10343; Radke et al, 2022, https://doi.org/10.1289/EHP11185; Carlson et al., 2024; https://doi.org/10.1289/EHP14191) and a 2023 evidence map on an additional 345 PFAS (Shirke et al. 2024, https://doi.org/10.1289/EHP13423 ). The comprehensive PFAS dashboard includes evidence identified from our past SEMs and completed US EPA assessments. This dataset is associated with the following publication: Shirke, A., E. Radke, R. Jones, B. Allen, C. Lin, A. Ross, N. Vetter, C. Lemeris, p. hartman, S. Eftim, A. Varghese, R. Blain, H. Hubbard, A. Williams, K. Thayer, and L. Carlson. Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 0(0): 1-45, (2025).

Resources

6 resources available

  • https://hawc.epa.gov/assessment/100500347/

    FILE
  • https://heronet.epa.gov/heronet/index.cfm/project/page/project_id/4214

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  • https://public.tableau.com/app/profile/literature.inventory/viz/ComprehensivePFASEvidenceMapVisualizations/ReadMe

    FILE
  • https://public.tableau.com/app/profile/literature.inventory/viz/PFASUniverseEvidenceMapVisualizations_17249628281260/ReadMe

    FILE
  • PFAS Universe Supplemental A Data_final.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
  • PFAS Universe Supplemental B Prioritization Datasets final.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET

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