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Support for Use of Naloxone and Other Opioid Overdose Reversal Medications to Prevent Overdose Deaths

Published by Substance Abuse and Mental Health Services Administration | U.S. Department of Health & Human Services | Catalog Last Checked: July 31, 2026 at 10:02 PM | Dataset Last Updated: September 06, 2025
Monitoring the distribution and impact of opioid overdose reversal medications such as naloxone is essential to optimizing overdose prevention strategies and improving public health outcomes. This Statistical Data Profile, the first to use performance data from two SAMHSA grant programs, examines the distribution of FDA-approved opioid overdose reversal medications, including naloxone/Narcan. The Data Profile also presents the training of first responders, community organization staff and other individuals to administer the reversal medications and provide other support services.

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