The Spitzer/MIPS 24 and 70 μm imaging of an 11.5 square degree region near the South Ecliptic Pole (SEP) has been carried out in order to complement sub-millimeter wavelength observations (250-500 μm) of the same region of sky taken with the Balloon-borne Large Aperture Sub-millimeter Telescope (BLAST), with the goal of better characterizing the nature of sub-millimeter selected galaxies and their role in galaxy evolution. This field has also been extensively mapped at other wavelengths, and will be imaged from 100-500 μm as part of the Herschel Multi-tiered Extragalactic Survey (HerMES). Source detection and photometry were performed using the APEX software within the MOPEX package. Source candidates with S/N > 6 and reduced chi-squared values less than or equal to three (93% of the sources) are considered reliable detections. The remaining source candidates were then inspected (see Scott et al. 2010 for details) and false positives were removed from the catalog.