This tabular data set represents Enhanced Vegetation Index compiled for two spatial components of the NHDPlus version 2.1 data suite (NHDPlusv2) for the conterminous United States; 1) individual reach catchments and 2) reach catchments accumulated upstream through the river network. This dataset can be linked to the NHDPlus version 2.1 data suite by the unique identifier COMID. Units are 0-1, 0 being low vegetation, 1 being high vegetation. Reach catchment information characterizes data at the local scale. Reach catchments accumulated upstream through the river network characterizes cumulative upstream conditions. Network-accumulated values are computed using two methods, 1) divergence-routed and 2) total cumulative drainage area. Both approaches use a modified routing database to navigate the NHDPlus reach network to aggregate (accumulate) the metrics derived from the reach catchment scale. (Schwarz and Wieczorek, 2016). Enhanced Vegetation Index were compiled by season for the fall of 2011, winter, spring, and summer of 2012. Seasons are defined as 1) fall: October, November, and December; 2) winter: January, February, and March; 3) spring: April, May, and June; and 4) summer: July, August, and September. Source data are derived from MODUS satellite imagery and were processed by the University of Oregon and provided as mean seasonal values for the conterminous United States.