Version 10.0 of these data are part of a larger U.S. Geological Survey (USGS) project to develop an updated geospatial database of mines, mineral deposits, and mineral regions in the United States. Mine and prospect-related symbols, such as those used to represent prospect pits, mines, adits, dumps, tailings, etc., hereafter referred to as “mine” symbols or features, have been digitized from the 7.5-minute (1:24,000, 1:25,000-scale; and 1:10,000, 1:20,000 and 1:30,000-scale in Puerto Rico only) and the 15-minute (1:48,000 and 1:62,500-scale; 1:63,360-scale in Alaska only) archive of the USGS Historical Topographic Map Collection (HTMC), or acquired from available databases (California and Nevada, 1:24,000-scale only). Compilation of these features is the first phase in capturing accurate locations and general information about features related to mineral resource exploration and extraction across the U.S. The compilation of 725,690 point and polygon mine symbols from approximately 106,350 maps across 50 states, the Commonwealth of Puerto Rico (PR) and the District of Columbia (DC) has been completed: Alabama (AL), Alaska (AK), Arizona (AZ), Arkansas (AR), California (CA), Colorado (CO), Connecticut (CT), Delaware (DE), Florida (FL), Georgia (GA), Hawaii (HI), Idaho (ID), Illinois (IL), Indiana (IN), Iowa (IA), Kansas (KS), Kentucky (KY), Louisiana (LA), Maine (ME), Maryland (MD), Massachusetts (MA), Michigan (MI), Minnesota (MN), Mississippi (MS), Missouri (MO), Montana (MT), Nebraska (NE), Nevada (NV), New Hampshire (NH), New Jersey (NJ), New Mexico (NM), New York (NY), North Carolina (NC), North Dakota (ND), Ohio (OH), Oklahoma (OK), Oregon (OR), Pennsylvania (PA), Rhode Island (RI), South Carolina (SC), South Dakota (SD), Tennessee (TN), Texas (TX), Utah (UT), Vermont (VT), Virginia (VA), Washington (WA), West Virginia (WV), Wisconsin (WI), and Wyoming (WY). The process renders not only a more complete picture of exploration and mining in the U.S., but an approximate timeline of when these activities occurred. These data may be used for land use planning, assessing abandoned mine lands and mine-related environmental impacts, assessing the value of mineral resources from Federal, State and private lands, and mapping mineralized areas and systems for input into the land management process. These data are presented as three groups of layers based on the scale of the source maps. No reconciliation between the data groups was done.