The PROSPER output rasters represent the estimates of probability of annual streamflow permanence produced by the PRObability of Streamflow PERmanence (PROSPER) model, for years 1989 through 2018, in the upper Missouri River Basin of the United States. The PROSPER model is a raster-based empirical model with outputs representing probabilistic predictions of an unregulated and minimally impaired stream channel in the upper Missouri River Basin, U.S. having year-round flow. This region includes 4-digit Hydrologic Unit Code boundaries 1002-1013. The model provides predictions at a 10-m spatial resolution based on monthly or annually updated values of basin climatic conditions and static physiographic variables upstream from a pixel cell along a stream network. Predictions are assigned to pixel cells on the channel network consistent with the high-resolution National Hydrography Dataset channel network stream grid.