Select photographic sequence of a Burmese Python (Python bivittatus) nesting in the wild within a concrete pipe from 01 June 2022 through 01 August 2022 in Big Cypress National Preserve within the Greater Everglades Ecosystem, Florida, USA. This python was tracked to an area of abandoned construction pipes and discovered inside to have oviposited. Throughout incubation, the python was observed to shift her coils, shiver to elevate body temperature, and yawns. Twice the wildlife camera captures a Virginia opossum (Didelphis virginiana) entering the pipe and quickly exiting. The python temporarily leaves her clutch after biologists enclose the nest pipe. After returning on top of her nest, she lays coiled around the nest for 12 more days, she eventually uncoils and leaves the clutch. Six days later, the clutch begins to hatch in the pipe and continued to hatch over the next 13 days. The hatching of this clutch has been documented as largest clutch size ever documented for a free-ranging Burmese Python which adds to our expanding knowledge of this invasive species. Photos were captured by U.S. Geological Survey equipment (Hyperfire 2, Reconyx, Holmen, Wisconsin, USA). Additional csv dataset included showcases range of temperatures in celsius collected by three sets of data loggers (IButton DS1922L Thermochron Data Logger) at three different locations. Each data logger set included one 11-bit data logger collecting a temperature once every 20 mins and one 8-bit data logger collecting temperature once every 40 minutes. The 11-bit data logger recorded temperature to three decimal places and the 8-bit data logger recorded temperature to one decimal place. One set of data loggers were placed inside the coils of the nesting female Burmese python, second set was placed 0 centimeters adjacent to the nesting python, and the third set was placed 40 centimeters adjacent to the nesting python.