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Patent AT-E401424-T1: [Translated] METHOD FOR IDENTIFYING NUCLEIC ACID LIGANDS FOR TISSUE TARGETS

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Catalog Last Checked: September 10, 2026 at 08:14 PM | Dataset Last Updated: September 06, 2025
This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to peripheral blood mononuclear cells (PBMC), fibrin clots and carotid arteries are described.

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