Patent AT-E401330-T1: [Translated] 2,3-OLEFINIC EPOTHILONE DERIVATIVES
The present invention relates to 2,3-position modified epothilone derivatives, methods of preparation of the derivatives, and intermediates therefor. The compounds of the invention as 16-membered macrolides having the general structure,which have microtubule-stabilizing effects and cytotoxic activity against rapidly proliferating cells, such as, tumor cells or other hyperproliferative cellular disease.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"009:25"
]
|
| contactPoint |
{
"fn": "NIH/NCBI Data Team",
"@type": "vcard:Contact",
"hasEmail": "mailto:info@ncbi.nlm.nih.gov"
}
|
| description | The present invention relates to 2,3-position modified epothilone derivatives, methods of preparation of the derivatives, and intermediates therefor. The compounds of the invention as 16-membered macrolides having the general structure,which have microtubule-stabilizing effects and cytotoxic activity against rapidly proliferating cells, such as, tumor cells or other hyperproliferative cellular disease. |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "Official Data Source",
"mediaType": "text/html",
"description": "Access the complete Patent AT-E401330-T1: [Translated] 2,3-OLEFINIC EPOTHILONE DERIVATIVES on the official website.",
"downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401330-T1"
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|
| identifier | https://healthdata.gov/api/views/wrwx-d9s3 |
| issued | 2025-09-05 |
| keyword |
[
"chemistry",
"innovation",
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"pubchem",
"research"
]
|
| landingPage | https://healthdata.gov/d/wrwx-d9s3 |
| modified | 2025-09-06 |
| programCode |
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"009:066"
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|
| publisher |
{
"name": "National Center for Biotechnology Information (NCBI)",
"@type": "org:Organization"
}
|
| theme |
[
"NIH"
]
|
| title | Patent AT-E401330-T1: [Translated] 2,3-OLEFINIC EPOTHILONE DERIVATIVES |
