Patent AT-E400301-T1: [Translated] ARTERIOVENOUS AND VENOUS TRANSPLANT TREATMENTS: METHODS AND COMPOSITIONS
A method and compounds are provided for inhibiting the synthesis of extracellular matrix proteins. Compounds of the invention comprise oligonucleotides specific for nuclear proto-oncogenes. Preferably, oligonucleotides of the invention are selected from the group consisting of c-myc and c-myb and are locally administered. The invention finds use in the treatment of a variety of disorders, including sclerotic disorders and restenosis, associated with the inappropriate synthesis of extracellular matrix proteins, particularly collagen.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "009:25" ] |
| contactPoint |
{ "fn": "NIH/NCBI Data Team", "@type": "vcard:Contact", "hasEmail": "mailto:info@ncbi.nlm.nih.gov" } |
| description | A method and compounds are provided for inhibiting the synthesis of extracellular matrix proteins. Compounds of the invention comprise oligonucleotides specific for nuclear proto-oncogenes. Preferably, oligonucleotides of the invention are selected from the group consisting of c-myc and c-myb and are locally administered. The invention finds use in the treatment of a variety of disorders, including sclerotic disorders and restenosis, associated with the inappropriate synthesis of extracellular matrix proteins, particularly collagen. |
| distribution |
[ { "@type": "dcat:Distribution", "title": "Official Data Source", "mediaType": "text/html", "description": "Access the complete Patent AT-E400301-T1: [Translated] ARTERIOVENOUS AND VENOUS TRANSPLANT TREATMENTS: METHODS AND COMPOSITIONS on the official website.", "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E400301-T1" } ] |
| identifier | https://healthdata.gov/api/views/mtsh-r6k4 |
| issued | 2025-09-05 |
| keyword |
[ "chemistry", "innovation", "patent", "pubchem", "research" ] |
| landingPage | https://healthdata.gov/d/mtsh-r6k4 |
| modified | 2025-09-06 |
| programCode |
[ "009:066" ] |
| publisher |
{ "name": "National Center for Biotechnology Information (NCBI)", "@type": "org:Organization" } |
| theme |
[ "NIH" ] |
| title | Patent AT-E400301-T1: [Translated] ARTERIOVENOUS AND VENOUS TRANSPLANT TREATMENTS: METHODS AND COMPOSITIONS |
