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Patent AT-E400296-T1: [Translated] COMPOSITIONS AND METHODS FOR STABILIZING BIOLOGICAL MOLECULES AFTER LYOPHILIZATION

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Catalog Last Checked: September 10, 2026 at 08:04 PM | Dataset Last Updated: September 06, 2025
The present invention is directed to compositions and methods for the preparation of biological molecules, in particular MenC-CRM 197. Biological molecules dissolved in dissolution buffers comprising at least one amorphous excipient and an amorphous buffer exhibit reduced aggregation and proteolytic breakdown.

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