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    • Patent AT-E400252-T1: [Translated] PHARMACEUTICAL SOLID DISPERSIONS

    Metadata Updated: September 8, 2025

    A composition comprises a solid dispersion comprising a low-solubility drug and at least one polymer. At least a major portion of the drug in the dispersion is amorphous. The polymer has a glass transition temperature of at least 100 DEG C measured at a relative humidity of fifty percent. Another aspect of the invention comprises the same composition except that the dispersion has a glass transition temperature of at least 50 DEG C at a relative humidity of fifty percent. In another aspect of the invention, a composition comprises a solid dispersion comprising a low-solubility drug and a stabilizing polymer. At least a major portion of the drug in the dispersion is amorphous. The composition also includes a concentration-enhancing polymer that increases the concentration of the drug in a use environment. The stabilizing polymer has a glass transition temperature that is greater than the glass transition temperature of the concentration-enhancing polymer at a relative humidity of 50%.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

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    Dates

    Metadata Created Date September 6, 2025
    Metadata Updated Date September 8, 2025

    Metadata Source

    Harvested from Healthdata.gov

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date September 6, 2025
    Metadata Updated Date September 8, 2025
    Publisher National Center for Biotechnology Information (NCBI)
    Maintainer
    Identifier https://healthdata.gov/api/views/edft-iebm
    Data First Published 2025-09-05
    Data Last Modified 2025-09-06
    Category NIH
    Public Access Level public
    Bureau Code 009:25
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Metadata Catalog ID https://healthdata.gov/data.json
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id ec668465-47b1-4c64-9252-94c57ab32d4d
    Harvest Source Id 651e43b2-321c-4e4c-b86a-835cfc342cb0
    Harvest Source Title Healthdata.gov
    Homepage URL https://healthdata.gov/d/edft-iebm
    Program Code 009:066
    Source Datajson Identifier True
    Source Hash 08084cd90c439fa2254c532da391fefd47ec13323ffdb0f9cbd9f5c0757fdc16
    Source Schema Version 1.1

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