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Ozone-induced changes in pulmonary metabolites in Humans

Metadata Updated: February 25, 2022

Dataset contains a list of metabolites, their fold change after ozone exposure and a p value for that change. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: This dataset can be accessed by contacting Dr. Robert Devlin ( Format: The dataset was sent to us by the company (Metabolon) that did the metabolite analysis, including the statistical analysis). It is an excel spreadsheet that contains a row for each of the metabolites that were identified, fold changes in each metabolite after air and ozone exposure (and the p value of the ozone-induced change), and the pathway and superpathway to which each metabolite belongs.

This dataset is associated with the following publication: Cheng, W., K. Duncan, A. Ghio, C. Ward-Caviness, E. Karoly, D. Diaz-Sanchez, R. Conolly, and R. Devlin. Changes in metabolites present in lung-lining fluid following exposure to humans to ozone. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163(2): 430-439, (2018).

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

Downloads & Resources

No file downloads have been provided. The publisher may provide downloads in the future or they may be available from their other links.



Metadata Created Date November 12, 2020
Metadata Updated Date February 25, 2022

Metadata Source

Harvested from EPA ScienceHub

Additional Metadata

Resource Type Dataset
Metadata Created Date November 12, 2020
Metadata Updated Date February 25, 2022
Publisher U.S. EPA Office of Research and Development (ORD)
Data Last Modified 2016-06-01
Public Access Level public
Bureau Code 020:00
Schema Version
Harvest Object Id e056028b-8fca-4545-82e3-0a01c31868b1
Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
Harvest Source Title EPA ScienceHub
Program Code 020:094
Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents
Source Datajson Identifier True
Source Hash 1bce23db927eb257469752f51f2bc73f2ffc4d27
Source Schema Version 1.1

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