This document is a supplement to the President's FY 2023 Budget Request to Congress. Following Congressional mandate, the Supplement incorporates budgetary and programmatic information for member agencies of the NITRD Program and for the National Artificial Intelligence Initiative. This report covers FY 2021 actual, FY 2022 enacted, and FY 2023 requested funding levels by agency and Program Component Area for all NITRD R&D programs. It also describes the key R&D programs and coordination activities planned for FY 2023 by the Federal agencies participating in NITRD. This Supplement reports specific agency investments for FYs 2021–2023 for AI and the National AI Research Institutes and for advanced wireless communications. A separate appendix, the FY 2023 Federal Cybersecurity R&D Strategic Plan Implementation Roadmap, lists existing and proposed R&D projects that address critical national cybersecurity needs (https://www.nitrd.gov/pubs/FY2023-Cybersecurity-RD-Roadmap.pdf).