A seismic hazard model for South America, based on a smoothed (gridded) seismicity model, a subduction model, a crustal fault model, and a ground motion model, has been produced by the U.S. Geological Survey. These models are combined to account for ground shaking from earthquakes on known faults as well as earthquakes on un-modeled faults. This data set represents the results of calculations of hazard curves for a grid of points with a spacing of 0.1 degrees in latitude and longitude. It represents Modified Mercalli Intensity (MMI) with a 10% probability of exceedance in 50 year. The maps and data were derived from PGA ground-motion conversions of Worden et al. (2012), and include soil amplification based on a topographic proxy of Allen and Wald (2009), and site amplification based on Seyhan and Stewart (2014) relationships.