These data were collected from the TOPGUN-SODA10 2AK core collected in 2010 by LacCore (University of Minnesota), the USGS. and the University of California (U.C.) Berkeley. The 8.9 meter length core had stable isotopes of oxygen and carbon sampled every 10 millimeters or so, and diatoms samples at every 50 millimeters to 200 millimeters depending on the depth in the core. mineralogic data were collected using X-ray diffraction and grain-size analysis were done at various depths. These data are used to interpret the Holocene and late Pleistocene hydrology and paleoclimate of the lake and the region. The interpretation can be found in: Rosen, M.R., Reidy, L., Starratt, S., Zimmerman, S., in review, Middle Holocene hydrologic changes in Big Soda Lake, Nevada, USA, caused by river avulsion. In Rosen, M.R., Finkelstein, D., Park-Boush, L., and Pla Plueyo, S. (eds.) Limnogeology: Progress, challenges and opportunities: A tribute to Beth Gierlowski-Kordesch, Syntheses in Limnogeology No. 2, Springer.