Abstract ======== The Mercury Dual Imaging System (MDIS) consists of two cameras, a Wide Angle Camera (WAC) and a Narrow Angle Camera (NAC), mounted on a common pivot platform. This dataset include regional mosaics of targeted observations directed at specific regions of interest. Four types of targeted observations are included: (a) WAC 3-color targeted observations acquired mainly during the primary mission, to complement 1 km/pixel 8-color mapping with a higher spatial resolution 3-color product; (b) WAC observations of targets that were observed repeatedly at different photometric geometries in order to improve photometric models of Mercury; these were observed initially in 8 color and since early 2013 in 11 colors; (c) WAC 8- or 11-color science targeted observations; and (d) NAC image strips acquired either for high-resolution imaging of morphology or as context for MASCS or MLA observations. The images in each observation share a common SITE_ID in the file name and PDS label. The SITE_ID corresponds to a targeting request entered into a database, in response to which a series of images was acquired. There is one SITE_ID for each time the region of interest is observed; thus for photometry targets, the same geographic region of interest is covered by many sets of images, each set sharing a common SITE_ID and distinct photometric geometry. Each mosaic is map projected in an orthographic projection, and contains one or more image planes. NAC mosaics contain 4 backplanes: observation ID, solar incidence angle, emission angle, and phase angle. WAC color products contain 3 backplanes: solar incidence angle, emission angle, and phase angle.