This data release provides inputs needed to run the LANDIS-II landscape change model, NECN and Base Fire extensions for the Greater Yellowstone Ecosystem (GYE), USA, and simulation results that underlie figures and analysis in the accompanying publication. We ran LANDIS-II simulations for 112 years, from 1988-2100, using interpolated weather station data for 1988-2015 and downscaled output from 5 general circulation models (GCMs) for 2016-2100. We also included a control future scenario with years drawn from interpolated weather station data from 1980-2015. Model inputs include raster maps (250 × 250 m grid cells) of climate regions and tables of monthly temperature and precipitation for each climate region. We provide initial conditions in 1987 as rasters and tables (i.e., species-age cohorts, aboveground biomass, soil carbon and nitrogen in surface litter 3 soil layers, soil percent sand, soil percent clay, soil wilting point, soil field capacity, soil drainage, soil storm flow and base flow fractions, and soil depth), historical fire data for model calibration, climate-inferred lognormal fire size distributions for each simulation year, and LANDIS-II control files including parameters for species and functional groups. Outputs from 10 replicates for each of 5 GCMs and the control scenario are provided as rasters and tables. Tables include spatially-weighted mean annual temperature and precipitation of the GYE for each GCM and the control scenario, summarize annual area burned by scenario, summarize biomass pools, and summarize changes in mean stand age. Rasters include annual simulated fire severity for 2015-2100, simulated total aboveground biomass in 4-year timesteps, aboveground biomass of all species in 4-year timesteps, stand age in 4-year timesteps, maximum and minimum cohort age for three dominant species (Pinus contorta, Picea engelmannii, and Pseudotsuga menziesii) in 4-year timesteps, forest type in 1988 and 2100, net ecosystem exchange in 2040 and 2100, and total ecosystem carbon in 4-year timesteps.