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Judson_Kleinstreuer_Development and Validation of a Computational Model for Androgen Receptor Activity.
Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity.
This dataset is associated with the following publication:
Kleinstreuer, N.C., P. Ceger, E. Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, and R. Judson. (Chemical Research in Toxicology) Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 30(4): 946-964, (2017).
Resources
1 resource available
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https://gaftp.epa.gov/Comptox/Staff/rjudson/publications/Kleinstreuer%20AR%20model%20CRT%202016/
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Richard Judson", "hasEmail": "mailto:judson.richard@epa.gov" } |
| description | Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity. This dataset is associated with the following publication: Kleinstreuer, N.C., P. Ceger, E. Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, and R. Judson. (Chemical Research in Toxicology) Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 30(4): 946-964, (2017). |
| distribution |
[ { "title": "https://gaftp.epa.gov/Comptox/Staff/rjudson/publications/Kleinstreuer%20AR%20model%20CRT%202016/", "accessURL": "https://gaftp.epa.gov/Comptox/Staff/rjudson/publications/Kleinstreuer%20AR%20model%20CRT%202016/" } ] |
| identifier | https://doi.org/10.23719/1503692 |
| keyword |
[ "ACToR", "High throughput screening", "ToxCast", "androgen receptor pathway", "computational model", "endocrine disruption screening" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-04-08 |
| programCode |
[ "020:095" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1021/acs.chemrestox.6b00347" ] |
| rights |
null
|
| title | Judson_Kleinstreuer_Development and Validation of a Computational Model for Androgen Receptor Activity. |
