This portion of the USGS data release describes the Delft3D-FLOW model application for propagating simulated tsunamis from 15 hypothetical earthquake sources of the Cascadia Subduction Zone through a series of nested grids to modeling tsunami sediment transport in the Salmon River estuary, OR. Input files necessary to run the Delft3D-FLOW model are provided. The model application was constructed using Delft3D-FLOW. Zip files containing model setup data are provided for each of the nested hydrodynamic grids at 1650 m, 400 m, and 50 m horizontal resolution. The fully three-dimensional sediment transport model at about 10 m resolution contains boundary condition files from the nested hydrodynamic grids for each of the earthquake scenarios, as well as bathymetry files reflecting different amounts of coseismic subsidence associated with the earthquake scenarios and adjusted to either Mean Low Water (MLW) hindcast for the 1700 CE earthquake or Mean Higher High Water (MHHW). Each zip file contains an example model run for the DOGAMI L3 earthquake source on each respective grid. These examples can be used as templates to run the other earthquake scenarios that are provided.