Digital flood-inundation maps for a 2.9-square-mile area of Ithaca, New York, were created in 2015–18 by the U.S. Geological Survey in cooperation with the City of Ithaca, New York, and the New York State Department of State. The flood-inundation maps depict estimates of the maximum areal extent and depth of flooding corresponding to selected flood frequencies for Cayuga Inlet, Sixmile Creek, Cascadilla Creek, and Fall Creek and selected water-surface elevations of Cayuga Lake. Flood profiles for the stream reaches were computed by combining a one-dimensional step-backwater model for the stream channels and a two-dimensional model for the overbank areas. The resulting hydraulic model was calibrated by using water-surface profiles from five observed storm events. The model was then used to compute 15 water-surface profiles for 5 flood frequencies (50- , 10- , 2- , 1- , and 0.2-percent annual exceedance probabilities, or 2- , 10- , 50- , 100- , and 500-year recurrence intervals) and 3 lake levels (representing average conditions, a 2-year-high condition, and a 100-year-high condition). The simulated water-surface profiles were then combined with a digital elevation model (derived from light detection and ranging data having 0.31-foot vertical accuracy and 3.3-foot horizontal resolution) to delineate the maximum area flooded at each water level. Flood-inundation maps and geographic information system flood-extent polygons and depth grids are available in the data release associated with this report . These maps can provide emergency management personnel and residents with information that is critical for flood-management planning, flood-response activities, and postflood recovery efforts.