This dataset contains genome-wide DNA methylation data from the Illumina EPIC array as well as information on the exposure given (clean air, diesel, or ozone) at each time point. Demographic and anthropomorphic information on the participants in the study is also included within the dataset. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: This data can be accessed by contacting the data owners. Access to the data requires an approved Institutional Review Board application from an appropriate institution. Format: This dataset include blood biomarker measurements (DNA methylation; Ilumina EPIC Methylation array) along with demographic and anthropomorphic information on participants. In addition there is data on which controlled exposure was received (clean air or diesel or ozone) and at which time points.

This dataset is associated with the following publications: Cardenas, A., R. Fadadu, L. Van Der Laan, C. Ward-Caviness, L. Granger, D. Diaz-Sanchez, M. Bind, and R. Devlin. Controlled Human Exposures to Diesel Exhaust: A Human Epigenome-Wide Experiment of Target Bronchial Epithelial Cells. Environmental Epigenetics. Oxford University Press, Cary, NC, USA, 7(1): dvab003, (2021). Bind, M., D. Rubin, A. Cardenas, R. Dhingra, C. Ward-Caviness, Z. Liu, J. Mirowsky, J. Schwartz, B. Coull, D. Diazsanchez, and R. Devlin. HETEROGENEOUS OZONE EFFECTS ON DNA METHYLOME OF BRONCHIAL CELLS: OBSERVED IN A CROSSOVER STUDY. Scientific Reports. Nature Publishing Group, London, UK, 10(1): 15739, (2020).