This is a dataset containing the first and second record of georeferenced observations of introduced and invasive vascular plant species in the contiguous United States (CONUS). Non-native plant species were identified using the United States Register of Introduced and Invasive Species (US-RIIS) list. After identifying a list of plants non-native to CONUS, we obtained presence data from aggregated occurrence databases, ensuring the occurrences we acquired were georeferenced (i.e., had coordinate information) and had an observation year recorded. We also identified and removed records that might indicate cultivation. From these data, the first and second record were removed and isolated. This data set contains the first record of 3,389 non-native plant species to CONUS, and where data were available, the second record as well.