Field spectra were collected from the Deschutes River near Bend, OR, July 26-28, 2016, to support research on remote sensing of river discharge. Reflectance measurements were made from a raft in the reach of the Deschutes River between Benham Falls and Dillon Falls using an Analytical Spectral Devices FieldSpec3 spectroradiometer operated in reflectance mode. The depth at each spectral measurement location was interpolated from field measurements of depth obtained with an echo sounder. This data release provides both the reflectance spectra and the interpolated depths and can be used to develop relationships between depth and reflectance for mapping river bathymetry from field spectra or passive optical remotely sensed data.