The U.S. Geological Survey (USGS) National Water Quality Network - Rivers and Streams (NWQN) comprises 117 surface-water monitoring sites designed to track ambient water-quality conditions across the nation. This dataset includes field quality-control results (field blank and field replicate concentrations), along with the water-quality result of each associated surface-water sample, of water samples collected from October 2012 through September 2017 at NWQN sites. This dataset includes 2 tables and 6 files of plots of the data. Tables are in Comma Separated Value, CSV, format and plotfiles are in Portable Document Format, PDF, format. The plotfiles are intended to provide a succinct view of the data. Table1.NWQNFieldBlanksC3.csv Table2.NWQNFieldReplicatesC3.csv PlotFile 1. Time-series plots showing concentrations of nutrients, carbon, UV absorbance, and suspended sediments in surface-water samples and field blanks in the National Water Quality Network, water years 2013–17. PlotFile 2. Scatterplots showing concentrations of pairs of surface-water samples and field replicates for nutrients, carbon, and suspended sediment in samples in the National Water Quality Network, water years 2013–17 . PlotFile 3. Time-series plots showing concentrations of major ions and trace elements in surface-water samples and field blanks in the National Water Quality Network, water years 2013–17. PlotFile 4. Scatterplots showing concentrations of pairs of surface-water samples and field replicates for major ions and trace elements in the National Water Quality Network, water years 2013–17. PlotFile 5. Time-series plots showing concentrations of pesticides in surface-water samples and field blanks in the National Water Quality Network, water years 2013–17. PlotFile 6. Scatterplots showing concentrations of pairs of surface-water samples and field replicates for pesticides in the National Water Quality Network, water years 2013–17.