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Effects of Oleic Acid on Human Endothelal Cells

Metadata Updated: November 12, 2020

Figure 1. Comparison of cell viability in response to exposure of cells to oleic acid (in ethanol), a hydroxy-metabolite, or methylated oleic acid as percent of the vehicle control response. Figure 2. Mitochondrial stress test extracellular flux using comparison of cellular oxygen consumption rate measures. Figure 3. Soluble mediator release comparison of cells exposed to oleic acid and its metabolites. Figure 4. Cellular iron-uptake following incubation with fatty acids. Supplement 2A. Lactate dehydrogenase activity release ( a measure of cell viability) is dose- and time-dependent. Supplement 2B. Oleic acid cellular association differs with vehicle utilized.

This dataset is associated with the following publication: Bass, V., J. Soukup, A. Ghio, and M. Madden. Oleic Acid and Derivatives Affect Human Endothelial Mitochondrial Function Cell and Vasoactive Mediator Production. Lipids in Health and Disease. BioMed Central Ltd, London, UK, 19(1): 128, (2020).

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

Downloads & Resources

References

https://doi.org/10.1186/s12944-020-01296-6

Dates

Metadata Created Date November 12, 2020
Metadata Updated Date November 12, 2020

Metadata Source

Harvested from EPA ScienceHub

Additional Metadata

Resource Type Dataset
Metadata Created Date November 12, 2020
Metadata Updated Date November 12, 2020
Publisher U.S. EPA Office of Research and Development (ORD)
Maintainer
Identifier https://doi.org/10.23719/1503700
Data Last Modified 2019-04-09
Public Access Level public
Bureau Code 020:00
Schema Version https://project-open-data.cio.gov/v1.1/schema
Harvest Object Id afe847d3-8ed8-4c17-b394-8938836edceb
Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
Harvest Source Title EPA ScienceHub
License https://pasteur.epa.gov/license/sciencehub-license.html
Program Code 020:094
Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents https://doi.org/10.1186/s12944-020-01296-6
Source Datajson Identifier True
Source Hash 70646795a794805f8c8afd076635c436a257f217
Source Schema Version 1.1

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