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Editorial comment

Published by National Institutes of Health | U.S. Department of Health & Human Services | Catalog Last Checked: September 10, 2026 at 08:26 PM | Dataset Last Updated: September 29, 2025
In this issue of the journal, Steinwaldet al[1] extend limited clinical studies and report an animal experiment showing that calcitonin precursors (predominantly procal-citonin) are elevated in proportion to the severity of bacterial sepsis. They conclude that procalcitonin, the major calcitonin precursor, is a good indicator of the activity and severity of the inflammatory response and may be used for monitoring bacterial infections.

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