A combination of discrete and daily-aligned groundwater levels for the Mississippi River Valley alluvial aquifer clipped to the Mississippi Alluvial Plain, as defined by Painter and Westerman (2018), with corresponding metadata are based on processing of U.S. Geological Survey National Water Information System (NWIS) (U.S. Geological Survey, 2020) data. The processing was made after retrieval using aggregation and filtering through the infoGW2visGWDB software (Asquith and Seanor, 2019). The nomenclature GWmaster mimics that of the output from infoGW2visGWDB. Two separate data retrievals for NWIS were made. First, the discrete data were retrieved, and second, continuous records from recorder sites with daily-mean or other daily statistics codes were retrieved. Each dataset was separately passed through the infoGW2visGWDB software to create a "GWmaster discrete" and "GWmaster continuous" and these tables were combined and then sorted on the site identifier and date to form the data products described herein. A sweep through the combined dataset (the "database") was made to isolate duplicate observations, or observations for the same well and on the same day. If a discrete value was present, it was retained as authoritative for the day and in descending order of priority daily-mean, daily-maximum, and daily minimum. Therefore, only a single record for a well and day are present in the dataset. The duplicate search removed 876 records and 31 wells were involved; in total, this is about 0.3 percent of the database. References: Asquith, W.H., Seanor, R.C., 2019, infoGW2visGWDB—An R groundwater data-processing utility for manipulating, checking the veracity, and converting an "infoGW" object to the "GWmaster" object for the visGWDB software with demonstration for the Mississippi River Valley alluvial aquifer: U.S. Geological Survey software release, Reston, Va., https://doi.org/10.5066/P9MK0B6L. Painter, J.A., and Westerman, D.A., 2018. Mississippi Alluvial Plain extent, November 2017: U.S. Geological Survey data release, https://doi.org/10.5066/F70R9NMJ. U.S. Geological Survey, 2020, USGS water data for the Nation: U.S. Geological Survey National Water Information System database, accessed April 2, 2020, at https://doi.org/10.5066/F7P55KJN.