The Networking and Information Technology Research and Development (NITRD) Program Digital Health Research and Development (DHRD) Interagency Working Group (IWG) held a federal-only workshop, 'Digital Health Lessons Learned During COVID-19', on August 9, 2022. Over eighty participants from nine Federal agencies took part in the workshop to underscore the opportunities and challenges facing digital health research and development (R&D). The goal of the workshop was to identify lessons learned about digital health during this public health crisis and the needs and opportunities for future research and development. Digital health has high potential to transform research and clinical practice as has been shown during the COVID-19 pandemic; however, there are challenges that should be addressed. This report identifies some of the challenges and opportunities that should be tackled in future digital health R&D and summarizes the key findings from the workshop.